The common genotyping rate was 0.97, and the average marker heterozygosity was 0.40. Single-marker analysis by means of the family-centered association check uncovered significant associations between podoconiosis and 7 of the 21 SNPs . Alleles of rs1063355, rs17612633, rs17612858, and rs17867526 demonstrated significant overtransmission in both additive and recessive versions. The major alleles of rs17843604 and rs9271100 demonstrated significant overtransmission in the recessive model, and the main allele of rs17211510 showed overtransmission in the additive model.U.S. Autism risk cited for pregnant women with flu A fresh study suggests being sick with the flu while pregnant can increase the risk of having a kid with autism. Teresa Garcia reviews. They found individuals that had among 15 specific CNVs in the Utah family members studies and 9 various other CNVs that had been in a custom-designed DNA array made from the family data got at least twice the opportunity of having an ASD when compared to control group. Individuals with one of 31 out of 185 CNVs that got previously reported to be linked to autism also showed this twice-as-likely chance. ‘These high-influence variants could be most readily useful in advising parents who curently have one child with an ASD,’ Hakonarson said.