2010;170:1013-1014. Obtainable pre-embargo to the media at.. Aggressive pursuit of low blood pressure, cholesterol levels might not benefit patients with diabetes A mathematical model shows that pursuing low blood circulation pressure and cholesterol levels might not benefit aggressively, and could even harm, some sufferers with diabetes, according to a written report in the June 28 problem of Archives of Internal Medicine, one of the JAMA/Archives journals. Almost all treatment recommendations for patients with diabetes recommend aggressively dealing with high low-density lipoprotein and blood pressure levels to lessen patients’ risk of developing heart disease, according to history information in the article.We report the outcomes of a randomized right now, controlled trial that was designed to determine the independent and combined effects of sustained weight reduction and regular exercise on physical function, body composition, and standard of living in obese old adults. We hypothesized that weight reduction and exercise would each improve physical function and that the combination of the two would result in the best improvement in physical function and amelioration of physical frailty.